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 | Pharmacology - various investigation fields |
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- AIDS (HIV), TSE (prions)
- Vaccines & adjuvants
- Neuro-degenerative disease (e.g. Immune response in multiple sclerosis)
- Allergy
- Inflammation
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| Pharmacokinetics & Metabolism - GLP studies |
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- Animal & human pharmacokinetics;
- Intracellular pharmacokinetics;
- In vivo & in vitro metabolism profile;
- Alternative in vitro models (human BBB, transporters, CYPs).
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| Bioanalysis for NCEs, peptides, polypeptides & proteins & oligonucleotides |
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- GLP development, validation of assays & drug measurement;
- Various techniques such as, HPLC-MS/MS, Immunoassay, competitive hybridization.
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| Microbiological Safety (HIV & prion) |
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- Assessment of manufacturing & purification processes as wells as detergents & sterilisation steps.
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| Biotransformation Platform for the Generation & Production of NCE & Metabolites |
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