(S)-AL 8810

Prostaglandins
Reference 10023

Data

	Molecular Formula	C24H31O4F
	Formulation	A crystalline solid
	Purity	>98%
	Stability	1 year
	Storage	-20°C
	Shipping	WET ICE
	Correlated Keywords	antangonists, FP, receptors, PGF2alpha, PGF2α, prostaglandins, analogs, C-15, epimers, (S)-AL-8810, (S)-AL8810, S-AL8810

Description

AL 8810 is an 11β-fluoro analog of PGF2α which acts as a potent and selective antagonist at the FP receptor. (S)-AL 8810 is the C-15 epimer of AL 8810, having the inverse, (S), or 'natural' configuration at C-15 relative to AL 8810, which is 15-(R). The pharmacology of (S)-AL 8810 has not been published.

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Documentation

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Articles

Griffen, B.W., Klimko, P., Crider, J.Y., et al. AL-8810: A novel prostaglandin F_2α analog with selective antagonist effects at the prostaglandin F_2α (FP) receptor. J Pharmacol Exp Ther 290 1278-1284 (1999).

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