 |  | | | | | (3S)-3-Hydroxyquinidine (3-OHquinidine) | Chemicals.metabolites | | Reference M02012 |  |
| | | Data |  | CAS number | 53457-23-5 | | Sub category | Metabolites | | Molecular Formula | C20H24N2O3 | | Molecular Weight | 340.4 | | Stability | ≥ 1 year | | Purity | ≥ 98% | | Application | CYP3A4 metabolite of Quinidine | | Storage | + 4°C | | Shipping | Wet Ice | | Contents | 1 ea | | Correlated Keywords | metabolites, metabolism, CYP450, CYP-450-3A4, CYP-3A4, CYP3A4, cytochromes, M02012 |
| | | Documentation | | | | | | In vitro metabolism of quinidine: the (3S)-3-hydroxylation of quinidine is a specific marker for cytochrome P4503A4 activity in human liver microsomes.
Nielsen T.L.et al. J. of Pharmacology and. Experimental Therapeutics 289, 31-37 (1999). | | (3S)-3-Hydroxyquinidine, the major biotransformation product of quinidine. Synthesis and conformational studies. X-ray molecular structure of (3S)-3-hydroxyquinidine methane sulfonate.
Caroll FI et al. J. Chem. Soc. Perkin Trans. I, 3017-3026 (1991). | | Microbiological transformation of quinidine.
Eckenrode FM. J. Nat. Prod. 47, 882-884(1984). |
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