 |  | | | | | (3S)-3-hydroxy-10,11-dihydroquinidine (3-OHDHquinidine) | Chemicals.metabolites | | Reference M02013 |  |
| | | Data |  | CAS number | 85405-59-0 | | Sub category | Metabolites | | Molecular Formula | C20H26N2O3 | | Molecular Weight | 342.4 | | Stability | ≥ 1 year | | Purity | ≥ 98% | | Application | CYP3A4 metabolite of 10, 11- dihydroquinidine | | Storage | + 4°C | | Shipping | Wet Ice | | Contents | 1 ea | | Correlated Keywords | metabolites, metabolism, CYP450, CYP-450-3A4, CYP-3A4, CYP3A4, cytochromes, M02013 |
| | | Documentation | | | | | | Potent inhibition of yeast-expressed CYP2D6 by dihydroquinidine, quinidine and its metabolites.
Ching MS et al. Biochem. Pharmacol. 50 (6), 833-837 (1995). | | Specific determination of hydroquinidine and its major metabolites in biological fluids by high performance liquid chromatography.
Resplandy G et al. J. Liquid Chromatogr. 11(7), 1495-1511 (1988). | | Pharmacokinetics of hydroxy-(3)-dihydroquinidine in healthy volunteers after intravenous and oral administration.
Jaillon P et al. Eur. J. Drug Metabol. Pharmacokin. 11(3), 233-238 (1986).Trenk D et al. | | Determination of the interaction of 3S-hydroxy-10,11-dihydroquinidine on the pharmacokinetics and pharmacodynamics of warfarin.
Arzneimittel Forschung 43(8), 836-841 (1993). |
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