(+)-2,5-epi-Goniothalesdiol

unclassified
Reference 10008887

Data

	Molecular Formula	C14H18O5
	Formulation	A solution in methyl acetate
	Purity	≥98%
	Stability	1 year
	Storage	-20°C
	Shipping	Wet Ice
	Correlated Keywords	tetrahydrofuran, cytotoxic, pesticide, anticancers, drugs, antitumor, styryl, lactone

Description

Goniothalesdiol, isolated from the bark of the Malaysian tree G. borneensis, is a tetrahydrofuran compound known to have significant cytotoxic effects against P388 murine leukemia cells and pesticidal activities. (+)-2,5-epi-Goniothalesdiol is a goniothalesdiol analog. Little is known of its biological activity.

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Documentation

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Articles

	Prasad, K.R., Gholap, S.L. Stereoselective synthesis of (+)-goniothalesdiol. J Org Chem 71 3643-3645 (2006).
	Prasad, K.R., Gholap, S.L. An expeditious enantiospecific total synthesis of (+)-7-epi-goniofufurone. Synlett 14 2260-2262 (2005).
	Blázquez, M.A., Bermejo, A., Zafra-Polo, M.C., et al. Styryl-lactones from Goniothalamus species-a review. Phytochem Anal 10 161-170 (1999).

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