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| Advanced Course on Biotransformation |
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 | Goal of the training |
| | | Our aim is to make participant able to better apprehend or improve his knowledge in Biotransformation reactions. These methods involve whole-cell microorganims to carry out reduction or oxydation (such as hydroxylation) reactions for the preparation of xenobiotics metabolites or New Chemical Entities (NCEs). |
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 | Participants |
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| This one day training course is dedicated to people from industry such as fine chemistry, cosmetology, pharmacy, agrochemistry...belonging to metabolism, chemical or drug discovery departments... |
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 | Date & Location |
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Dates : contact us for further information SPI-BIO Parc d'Activités du Pas du Lac 10 bis avenue Ampère F-78180 Montigny le Bretonneux Tel: +33 139 306 260 - Fax: +33 139 306 299 |
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 | Fee |
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Admission fee: 800 Euros SPI-BIO is recognised as a training organism by the French authorities under the No11788021778. |
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 | Documentation |
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| During this course, a technical documentation will be supplied to participants. This documentation will enclose case studies and copy of the presentation slides. |
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 | Speakers |
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| This training workshop will be run by: |
- Mr. Christophe Créminon, scientific belonging to the Pharmacology & Immunology Dpt. From the French Atomic Energy Commission.
- Dr. Claude Bensoussan, former head of biotransformation and biocatalysis department at Aventis Pharma and Rhodia. After being CSO of Enzynomics, Dr. Bensoussan has founded BioAdvice (www.bioadviceonline.com) a company of Contract Operational Manager specialising in Biotech Industries.
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 | Program |
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|  | Welcome |  | |  | Theoretical introduction The goal of this section is to help participant to answer to the following crucial questions: - Why using microorganisms
- How to handle them
- The limiting factors and how to face them
|  | |  | Case studies From recent cases depicted in the scientific literature: - we will analyse the opportunity to resort to microorganisms
- we will assess the performances obtained compared to the traditional methods and taking into account the limits of the proposed method.
- the study cases will comprise the reduction & hydroxylation methods.
|  | |  | Lunch |  | |  | Methodological approaches We will explore the different steps from screening to preparative |  | |  | Experience of an Industrial people |  | |  | Discussion and conclusion |
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